SAVA - Cassava Sciences 02:14 AM - Jun 13 2021
by: Maverick

SAVA - Cassava Sciences - DD - June 2021

Current Price (June 13): 77
O/S 40M
Float 38M
Market cap: ~$3B
Cash ~280M
Burn/year: ~$25M

cassavasciences.com

AD drug - cassavasciences.com/simufilam

Importantly, we do not seek to clear amyloid out of the brain. Our science is based on stabilizing a critical protein in the brain.

Simufilam is a proprietary, small molecule (oral) drug that restores the normal shape and function of altered filamin A (FLNA), a scaffolding protein, in the brain.


They also have a blood test to detect AD cassavasciences.com/pti-125dx

Recent updates


Upcoming catalysts
  • See stonks.chat/feed/catalysts - they have them in June, July, August, September
  • Second interim analysis due to be presented July 26-29 at AAIC meeting.
  • They haven't had any news yet in June, so I'm sure an update of some sort is coming.  May was a whopper of an update, though.
  • Phase 3 study of simufilam in Alzheimer's disease starts in 2nd half 2021.

Heads up
As always, there's two major warnings with any biotech: data could turn out bad (despite expectations otherwise) and offerings are ever looming (since most biotechs have no revenue).

My Notes
This one has a lot going for it, but $3B feels like a hefty valuation at this stage based on what I currently new (though I'm new on this one). I need to do a little more homework.  I've traded this a few times, but I'll likely have a position going into summer data releases (starting in July).
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Maverick - 2 years ago
Update PR on June 21, 2021


  • Open-label Study Completes Patient Enrollment
  • Cognition Maintenance Study Initiated May 2020, now 30% Enrolled
  • 6-month Biomarker Data to be Presented at AAIC Conference in July
  • 9-month Safety & Cognition Data to be Presented at AAIC Conference 
  • Clinical Results with SavaDx to be Presented at AAIC Conference
  • Phase 3 Program Initiation Remains On-track for 2nd Half 2021
Maverick - 2 years ago
Maverick - 2 years ago
May 2021 Investor Presentation (must read) - cassavasciences.com/static-fil...

Cassava Sciences - SAVA

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